Overview
Stay current with the latest Small Fiber Neuropathy research. We collect new studies, clinical trials, and expert findings in one place. This page updates regularly with fresh discoveries and breakthroughs.
Latest Research
From Pain-Centric to Multi-Symptom Small Fiber Neuropathy
August 25th, 2025This study aimed to characterize the symptomatic variability of SFN and determine whether patients can be stratified into clinically meaningful subgroups.

Low Dose Naltrexone Shows Promise for SFN
August 20th, 2025LDN may improve symptoms in cryptogenic SFN, especially sensory and autonomic domains.

Peripheral Neuropathy in POTS: GI Symptom Links
July 3rd, 2025Study finds small and large fiber neuropathy in Swedish POTS patients, with links to GI symptoms.

Ibudilast For ALS: Combat-ALS Study
May 8th, 2025Phase 2b/3 trial tests MN-166 for ALS over 12 months, followed by 6-month open-label extension.

FDA Clears ST-503 for Neuropathic Pain Trials
December 14th, 2024FDA clears Sangamo’s ST-503 for Phase I/II trial in idiopathic SFN and chronic neuropathic pain.

Written by the SFN Foundation
August 26, 2025
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